Endocrine Abstracts

Aminobisphosphonates impair osteoclast cell function and reduce bone remodelling rate. It has been speculated that atypical femoral fractures in patients on bisphosphonates are the result of impaired bone remodelling.The primary aim of this prospective study was to assess levels of bone remodelling in patients with osteoporosis on aminobisphosphonate therapy by measurement of bone turnover markers. The secondary aim was to assess the adequacy of concomit...